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Showing posts with the label Acute and Chronic inflammation

Inflammation

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Inflammation:      It is a physiological process that is expressed by our immune system and may convert to pathological conditions in the future based on the severity of the inflammation.      It is classified into Acute and chronic inflammation based on the components of the inflammatory process. Inflammatory mediators: These are the chemical compounds that initiate and maintain the inflammatory process. 1. Arachidonic acid metabolites:      Arachidonic acid is released from the cell membrane by phospholipase A2. Then it will react with cyclooxygenase or 5-lipoxygenase enzymes.          - Arachidonic acid with cyclooxygenase produces prostaglandins (PG), which mediate vasodilation.          - Arachidonic acid with 5-lipoxygenase produces leukotrienes (LT), which mediates vasoconstriction and bronchospasm. 2. Mast cells: Mast cells are activated by any trauma and by complement proteins C3...