Pathophysiology of COVID 19
Introduction: COVID 19 is a viral respiratory disease that is able to cause systemic inflammatory response syndrome from the lungs. This virus was originated from China and it can spread through cough and fecal matter from an infected person. In this blog, I explain the clear pathophysiology of this disease. Basically, COVID 19 is caused by Coronavirus. Microbiologically it is a positive single-strand RNA virus (+ ss RNA). It is a complex virus which means it has a capsid inside the envelope. As the name indicates, Coronavirus have spikes in the envelope. It is the largest RNA virus in which the genome is approximately 30 kb. Coronavirus have nucleoprotein (capsid) around the RNA which is called N protein. The lipid bilayer membrane is covered as an envelope (E protein). The envelope has glyc...